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  • May 12, 2022

We've already got blue light Suzukis and and conjugate additions, and reductive couplings and Buchwalds and ... yadda yadda yadda, but you know what haven't got yet? A photoredox version of the Nozaki Kishi Hiyama - and two smart groups figured out that would be a smart thing to do and came to a solution at just about the same time. I'll let you decide who did it better.

This one published yesterday.

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My only comment on this one is really you couldn't have tried it with 4CzIPN (PC1 is the monocyano version of that)? I mean nobody wants to make the catalyst and I can't find anybody who currently sells 1469700-24-0.

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And this is the other one that published today. L3 is this, and HE is the Hantszch ester. Kessil currently has a 390 and 427... both would likely work with this reaction in the Lighning.

 
 
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